2009-09-14

抗H1N1新藥 藥廠稱無抗藥性

正當抵抗新流感藥物特敏福出現抗藥性之際,生物科技公司NexBio Inc.稱,

實驗性新藥Fludase可對抗新流感H1N1,同時亦可抗拒流感病毒變種,

令新藥不會出現抗藥性。醫院藥劑師學會教育資源中心總監崔俊明表示,

若在臨床能證明新藥不會出現抗藥性,這將是很大的突破。


研發公司:

老鼠實驗成功

     NexBio Inc.在三藩市 舉辦的美國 抗微生物製劑和化療會議上發表上述報告。

報告指在老鼠身上的實驗發現,Fludase影響流感病毒授體,令病毒不能黏附在人類的細胞,

令病毒不能進入人體,新藥亦不受病毒變種影響,故不會出現抗藥性。

新藥亦可以治療季節性流感。

治新流感藥特敏福和樂感清,都有抑制流感病毒表面蛋白原(神經氨酸酶)複製病毒作用,

以阻止流感病毒離開細胞,但當病毒變種時,卻會受影響而出現抗藥性。另外兩種對抗禽流

用藥amantadine和rimantadine治療效果微弱,而特敏福在去年亦出現抗藥性。

專家:

需時間證明藥效崔俊明說,若臨床證明新藥不會出現抗藥性,這會是很大的突破,但現時新

藥只在老鼠實驗證明,不排除新藥應用到人身上會出現問題,

故要等臨床試驗有結果才可證明藥效,但等新藥面世相信還有一段時間。

■昨日確診﹕580宗(313男 267女、4個月至69歲) 累積確診﹕18,098

2009-05-03

Maps of the spread of influenza A(H1N1)




Maps of the spread of influenza A(H1N1)






As of 3 May 2009, 16:00 GMT




As of 3 May 2009, 08:00 CET

PigFluMasks "bird flu"

What is avian influenza?


Avian influenza, or “bird flu”, is a contagious disease of animals caused by viruses that normally

infect only birds and, less commonly, pigs.

Avian influenza viruses are highly species-specific, but have, on rare occasions, crossed the species

barrier to infect humans.

In domestic poultry, infection with avian influenza viruses causes two main forms of disease,

distinguished by low and high extremes of virulence.

The so-called “low pathogenic” form commonly causes only mild symptoms

 (ruffled feathers, a drop in egg production) and may easily go undetected.

The highly pathogenic form is far more dramatic.

It spreads very rapidly through poultry flocks, causes disease affecting multiple internal organs,

and has a mortality that can approach 100%, often within 48 hours.

swineflu

Influenza A(H1N1) - update 12

3 May 2009 -- As of 1600 GMT, 3 May 2009, 18 countries have officially reported 898 cases of

influenza A(H1N1) infection.

Mexico has reported 506 confirmed human cases of infection, including 19 deaths. The higher

number of cases from Mexico in the past 48 hours reflects ongoing testing of previously collected

specimens. The United States Government has reported 226 laboratory confirmed human cases,

including one death.

The following countries have reported laboratory confirmed cases with no deaths

- Austria (1), Canada (85), China, Hong Kong Special Administrative Region (1), Costa Rica (1),

Denmark (1), France (2), Germany (8), Ireland (1), Israel (3), Italy (1), Netherlands (1), New Zealand
(4), Republic of Korea (1), Spain (40), Switzerland (1) and the United Kingdom (15).

Further information on the situation will be available on the WHO website on a regular basis.

WHO advises no restriction of regular travel or closure of borders.It is considered prudent for people

who are ill to delay international travel and for people developing symptoms following international

travel to seek medical attention, in line with guidance from national authorities.

Canada on 2 May reported the identification of the A(H1N1) virus in a swine herd in Alberta. It is

highly probable that the pigs were exposed to the virus from a Canadian farm worker recently

returned from Mexico, who had exhibited flu-like symptoms and had contact with the pigs. There is

no indication of virus adaptation through transfer from human to pigs at this time.

There is no risk of infection from this virus from consumption of well-cooked pork and pork
products.

Individuals are advised to wash hands thoroughly with soap and water on a regular basis and should

seek medical attention if they develop any symptoms of influenza-like illness.

Related links
Influenza A(H1N1) web site
Daily updates will be posted on this site.

Swine Flu

Swine Flu
Purple marker is confirmed or probable
Pink marker is suspect
Yellow marker is negative
Fatal cases have no dot

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